IMMUNOGENIC COMPOSITIONS PREPARED FROM TUMOR CELLS DERIVED FROM PERIPHERAL BLOOD AND ORIGINATING FROM A SOLID TUMOR AND THEIR USE

摘要

The described invention provides an immunopotent tumor-specific cancer cell product containing an immunogenic composition containing an immunostimulatory amount of an isolated population of dendritic cells contacted ex vivo with a cancer- specific cancer stem cell derived from a tumor cell, a tumor cell cluster, a tumor cell aggregate or a combination thereof expressing at least one cancer-specific antigen, the tumor cell, tumor cell cluster, tumor cell aggregate or the combination thereof being derived from peripheral blood; and an adjuvant; and a pharmaceutically acceptable carrier; as well as methods for preparing and using same.