PHARMACEUTICAL COMPOSITION FOR INHIBITING VASCULAR CALCIFICATION, CONTAINING DPP-4 INHIBITOR AS ACTIVE INGREDIENT

摘要

The present invention relates to: a composition for inhibiting vascular calcification, containing a dipeptidyl peptidase-4 (DPP-4) inhibitor as an active ingredient; a composition, containing DPP-4, for screening for inhibitors of vascular calcification; and a method for screening for inhibitors of vascular calcification by using the same. According to the present invention, the DPP-4 inhibitor can effectively inhibit vascular calcification, and thus can be applied as a therapeutic agent capable of preventing or treating various adult diseases such as cardiovascular disease, renal disease, and aging, which are related to vascular calcification, and the DPP-4 protein and gene can be effectively used for screening in the development of novel drugs for inhibiting vascular calcification.