首页> 外国专利> Phamaceutical Compostions for Preventing and Treating Vascular Endothelial Cell Dyfunction Comprising Nafamostat Mesilate

Phamaceutical Compostions for Preventing and Treating Vascular Endothelial Cell Dyfunction Comprising Nafamostat Mesilate

机译:用于预防和治疗包含甲磺酸萘法莫他的血管内皮细胞功能障碍的药物组合物

摘要

The present invention relates to a pharmaceutical composition for preventing and treating vascular endothelial cell disease comprising nafamostat mesilate as an active ingredient. The pharmaceutical composition according to the present invention has an anti-inflammatory effect of vascular endothelial cells by blocking the inflammatory reaction mechanism by TNF-a of vascular endothelial cells and exhibits vasorelaxant effect. Thus, the pharmaceutical composition for vascular inflammation diseases and vasoconstriction Can be used as the composition.
机译:本发明涉及用于预防和治疗血管内皮细胞疾病的药物组合物,其包含甲磺酸萘法莫他作为活性成分。本发明的药物组合物通过阻断血管内皮细胞的TNF-α的炎症反应机制而具有血管内皮细胞的抗炎作用,并显示血管舒张作用。因此,可以将用于血管炎症疾病和血管收缩的药物组合物用作组合物。

著录项

  • 公开/公告号KR101579133B1

    专利类型

  • 公开/公告日2015-12-21

    原文格式PDF

  • 申请/专利权人 충남대학교 산학협력단;

    申请/专利号KR20140003000

  • 发明设计人 김국성;송희정;강민웅;

    申请日2014-01-09

  • 分类号A61K31/245;A61P29;

  • 国家 KR

  • 入库时间 2022-08-21 14:15:26

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