首页> 外国专利> COMPOSITION FOR PREVENTING HAIR LOSS OR ACCELERATING HAIR GROWTH COMPRISING ADULT STEM CELL CULTURE DERIVED FROM HUMAN SKIN DERMIS

COMPOSITION FOR PREVENTING HAIR LOSS OR ACCELERATING HAIR GROWTH COMPRISING ADULT STEM CELL CULTURE DERIVED FROM HUMAN SKIN DERMIS

机译:包含源自人皮肤真皮的成年干细胞培养的防止脱发或促进毛发生长的组合物

摘要

Disclosed in the present invention is a new usage of adult stem cell culture derived from the human skin dermis. A composition containing culture of adult stem cells (human dermal stem/progenitor cells, hereafter hDSPCs) derived from the human skin dermis as an active component comprises the increased amount of transcriptomes of Wnt genes or Wnt proteins compared with culture of fibroblasts derived from the human skin dermis. Accordingly, the composition accelerates Wnt/-catenin signal transmission, increases propagation or differentiation of skin dermal papilla cells or controls aging, and increases expression or activity of a growth factor and the like, thereby having an effect of preventing hair loss or accelerating hair growth.
机译:本发明公开了源自人皮肤真皮的成人干细胞培养物的新用途。包含衍生自人皮肤真皮的成年干细胞(人类真皮干/祖细胞,下文称为hDSPCs)培养物作为活性成分的组合物,与衍生自人的成纤维细胞培养物相比,包含更多数量的Wnt基因或Wnt蛋白转录组。皮肤真皮。因此,该组合物促进Wnt /-连环蛋白信号传递,增加皮肤真皮乳头细胞的繁殖或分化或控制衰老,并增加生长因子等的表达或活性,从而具有防止脱发或促进头发生长的作用。 。

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