HYDROGEL CONTAINING ALBUMIN AND POLY ETHYLENE GLYCOL, AND MANUFACTURING METHOD THEREOF

摘要

The present invention relates to a kind of hydrogel and its manufacturing methods. According to the present invention, the hydrogel can be gelled, without side reaction, enter in vivo when injection is identical, since the fast reaction sulfydryl group culture albumin and polyethylene glycol (PEG) that are related between thioether bond have terminal maleimide and additional four arms. More specifically, drug is avoided in hydrogel, to prevent drug release by filling protein drug to the adhesive force of hydrogel. Therefore, the present invention relates to hydrogel, which adverse effect minimizes ontology by biocompatible material. ;The 2016 of copyright KIPO submissions