SYSTEMS AND METHODS FOR ESTIMATING PHYSIOLOGICAL HEART MEASUREMENTS FROM MEDICAL IMAGES AND CLINICAL DATA

摘要

Methods and systems for estimating physiological heart measurements from medical images and clinical data are disclosed. Patient-specific anatomical models of the heart are generated from the patient ' s medical image data. The patient-specific multi-physics computed cardiac model can be applied to patient-specific anatomical models by personalizing parameters of the cardiac electrophysiology model, cardiac biomechanical model, or cardiac hemodynamic model based on the patient ' s medical image data and clinical measurements . The patient's cardiac function is simulated using a patient-specific multi-physics computed cardiac model. The parameters may be personalized by inverse problem algorithms based on forward model simulations or the parameters may be personalized using a machine-learning based statistical model.