OVER-EXPRESSION OF A FATTY ACID TRANSPORTER GENE AND OF GENES ENCODING ENZYMES OF THE BETA-OXIDATION PATHWAY FOR HIGHER PRODUCTION OF RIBOFLAVIN VIA FERMENTATION OF EREMOTHECIUM

摘要

The present invention relates to a method for producing riboflavin in a genetically modified organism of the genus Eremothecium comprising culturing the organism in a culture medium and isolating riboflavin from the culture medium, Is linked to fatty acid uptake and / or beta-oxidation pathways of the organism. The present invention further relates to a method of providing an organism which accumulates riboflavin belonging to the genus Eremothecium by genetically modifying an organism belonging to the genus Eremothecium, as well as the organism obtained by this method , And the use of these genetically modified organisms to increase the accumulation of riboflavin.