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ORF2086 - NON-LIPIDATED VARIANTS OF NEISSERIA MENINGITIDIS ORF2086 ANTIGENS

机译:ORF2086-猪奈瑟球菌非脂化变体ORF2086抗原

摘要

The present invention relates to a composition comprising an isolated, non-fulvylated and non-lipidated ORF2086 polypeptide and a related method. In an exemplary embodiment, the compositions described herein exhibit immunogenicity. In addition, the present invention relates to compositions and related methods for eliciting a bactericidal immune response against mammalian ORF2086 subfamily B polypeptides from the serogroup B Naceria meningitidis.
机译:本发明涉及包含分离的,未富酰化的和非脂化的ORF2086多肽的组合物和相关方法。在一个示例性的实施方案中,本文所述的组合物表现出免疫原性。另外,本发明涉及引发针对来自血清群B脑膜炎奈瑟氏菌的哺乳动物ORF2086亚家族B多肽的杀菌免疫应答的组合物和相关方法。

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