Capsule containing mini-tablets comprising mosapride citrate for sustained-releasing formulation improving gastrointestinal disease and preparing the method thereof

摘要

In the case of the capsule preparation containing the simfried citrate of the present invention, there is no fear of arrhythmia and cardiogenic sudden death, and there is no side effects such as central nervous system side effect and hyperprolactinemia, so that it can be safely used. In addition, the manufacturing process is simple as compared with the conventional biodegradable or capsule preparation, and the active ingredient is filled in the capsule unlike ordinary tablets, so that there is little risk of contamination and deterioration by microorganisms and the like. It has the effect of having a pattern similar to the dissolution profile shown in the double column.