HAS2 Composition comprising HAS2 inhibitor for enhancing radiation sensitivity

摘要

The present invention relates to a composition for enhancing radiation sensitivity, and more particularly to a composition for enhancing radiation sensitivity comprising a HAS2 (Hyaluronan Synthase 2) inhibitor, particularly an antisense nucleic acid molecule which binds complementarily to a HAS2 base sequence, And more particularly, to a method for enhancing the radiation sensitivity of cancer cells, particularly cancer cells that have become radiation resistant. The radiation sensitivity-enhancing composition comprising the HAS2 inhibitor according to the present invention can enhance the radiation sensitivity of cancer cells, thereby enhancing the effect of radiation therapy in various cancer treatments having increased radiation resistance.