2 ---3-56--4-321--1--4-1--3--25- A COMPOSITION COMPRISING --TRANS-3-56-DIHYDRO-4H-PYRROLO321-IJQUINOLIN-1-YL-4-1H-INDOL-3-YLPYRROLIDINE-25-DIONE IN COMBINATION WITH A SECOND ANTI-PROLIFERATIVE AGENT

摘要

The present invention provides a method of treating a cell proliferative disease in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or a pyrroloquinolinyl-pyrrolidine- In combination with a therapeutically effective amount of a second anti-proliferative agent to treat a cell proliferative disease such as cancer.