Solid preparations containing choline alfoscerate and preparing method thereof

摘要

The present invention relates to a solid preparation and a preparation method thereof comprising a, choline alpo three acrylate and calcium silicate to calcium silicate is possible upset formulated in solid form by adsorbing the choline alpo three rates. In the case of the solid preparation containing the choline alpo three acrylate and calcium silicate of the present invention, or as compared to soft capsule formulations deterioration by microorganisms, less concern is the stability by a moisture-reduced, there is an excellent bulky smaller taking convenience advantages . In addition, the present invention by improving the initial dissolution rates of the solid preparation using a mixture of two or more of disintegrants, there is no difference in the expression of surface of the drug because they represent the level of the elution profile equivalent to the conventional soft capsule dosage form.