首页> 外国专利> - - Method for analyzing Ubiquitin-proteasome activity and screening method of Ubiquitin-proteasome inhibitor using the same

- - Method for analyzing Ubiquitin-proteasome activity and screening method of Ubiquitin-proteasome inhibitor using the same

机译:分析泛素蛋白酶体活性的方法和使用泛素蛋白酶体抑制剂的筛选方法

摘要

Provided are a method for quantitatively analyzing ubiquitin-proteasome activity with respect to a target polypeptide, and a method for screening a ubiquitin-proteasome inhibitor. According to the provided methods, a lysis pattern of a target polypeptide by ubiquitin-proteasome in target cells can be quantitatively analyzed in a rapid and highly sensitive way; a ubiquitin-proteasome inhibitor can be screened in a rapid and highly sensitive way; and an anticancer agent and the activity thereof can be rapidly screened.;COPYRIGHT KIPO 2016
机译:提供了定量分析针对靶多肽的泛素-蛋白酶体活性的方法,以及筛选泛素-蛋白酶体抑制剂的方法。根据提供的方法,可以以快速且高度灵敏的方式定量分析靶细胞中遍在蛋白-蛋白酶体对靶多肽的裂解模式。泛素-蛋白酶体抑制剂可以快速,高度敏感的方式进行筛选;并可以快速筛选抗癌药及其活性。; COPYRIGHT KIPO 2016

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