-1 Peptide analog binding to polo-box domain of polo-like kinase-1 and pharmaceutical composition for anti-cancer containing thereof

摘要

The present invention relates to a novel peptide analogue, or a stereoisomer or pharmaceutically acceptable salt thereof, and more particularly to a novel peptide analogue, or a stereoisomer or a pharmaceutically acceptable salt thereof, for an anticancer composition. The novel peptide analogue, or a stereoisomer or pharmaceutically acceptable salt thereof, is characterized by high affinity and selective binding to the poloxane domain of polo-like phosphorylase-1, and inhibits the activity of polo-like phosphorylase-1 And can be utilized as an excellent anticancer composition.