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DEUTERED THIAZOLIDININE ANALOGUES AS FOLICULOSTIMULATING HORMONE RECEPTOR AGONISTS
DEUTERED THIAZOLIDININE ANALOGUES AS FOLICULOSTIMULATING HORMONE RECEPTOR AGONISTS
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机译:氘代噻唑烷酮类似物作为叶酸刺激激素受体激动剂
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摘要
1. The deuterated thiazolidinone derivative according to formula (I) (I), wherein each Y is independently selected from the group consisting of hydrogen (H), deuterium (D); X is selected from the group consisting of S, sulfoxide; R, R are independently selected from the group consisting of hydrogen (H), deuterium (D), methyl, CHD, CHD, CD, ethyl, CHDCH, CHDCHD, CHDCHD, CHDCD, CDCH, CDCHD, CDCHD, CDCD; provided that at least one Y represents deuterium (D), or at least one of R, R contains at least one deuterium (D); optionally at least one carbon atom kind independently zamenenC; and its physiologically acceptable salts, solvates, tautomers and stereoisomers thereof, including mixtures thereof in all sootnosheniyah.2. The deuterated thiazolidinone derivative of claim 1, wherein at least one carbon atom is replaced by C; and its physiologically acceptable salts, solvates, tautomers and stereoisomers, including mixtures thereof in all ratios. 3. The deuterated thiazolidinone derivative according to any one of paragraphs. 1 or 2, where Y, Y, Y, Y are deuterium (D); and its physiologically acceptable salts, solvates, tautomers and stereoisomers, including mixtures thereof in all ratios. 4. The deuterated thiazolidinone derivative according to any one of paragraphs. 1-3, where Y, Y, Y, Y, Y are deuterium (D); and its physiologically acceptable salts, solvates, tautomers and stereoisomers, including mixtures thereof in all ratios. 5. The deuterated thiazolidinone derivative of claim 1, wherein Y, Y, Y, Y are deuterium (D); and its physiologically acceptable salts, solvates, tautomers and stereoisomers, including mixtures thereof in all ratios. 6. The deuterated thiazolidinone derivative of claim 1, wherein R 1 and R 2 are CD; and its physiologically acceptable salts, solvates, tautomers and stereoisomers, including
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