首页> 外国专利> MEDICINE FOR TREATMENT OF ACUTE MYELOID LEukemia (AML)

MEDICINE FOR TREATMENT OF ACUTE MYELOID LEukemia (AML)

机译:治疗急性髓性白血病(AML)的药物

摘要

1. A drug for the treatment of acute myeloid leukemia (AML), including a suspension of red blood cells with asparaginase encapsulated in them as an active component. The medicine according to claim 1, wherein one dose of the suspension comprises from 50 to 500 IU of encapsulated asparaginase per kg body weight. The medicine according to claim 1, wherein one dose of the suspension comprises from 50 to 200 IU of encapsulated asparaginase per kg body weight. The medicine according to claim 1, wherein one dose of the suspension comprises from 80 to 170 IU of encapsulated asparaginase per kg body weight. The drug according to any one of paragraphs. 1-4, where the patient is a child, adult or elderly person. 6. The medicament according to claim 5, wherein the patient does not tolerate standard treatment. A method for treating acute myeloid leukemia (AML), comprising administering an effective amount of a suspension of red blood cells with asparaginase encapsulated therein. 8. A method for treating acute myeloid leukemia (AML), comprising administering an effective amount of a suspension of red blood cells with asparaginase encapsulated in them, where one or more doses of the suspension are administered to the patient in the induction phase. A method of treating acute myeloid leukemia (AML), comprising administering an effective amount of a suspension of red blood cells with an asparaginase encapsulated in them, where one or more doses of the suspension are administered to the patient during the treatment phase and where one dose of the suspension comprises from 50 to 500 IU of encapsulated asparaginase per kg body weight .10. The method according to claim 9, wherein one dose of the suspension comprises from 50 to 200 IU of encapsulated asparaginase per kg body weight. The method of claim 9, wherein the single dose of the suspension comprises from 80 to 170 IU of encapsulated asparaginase per kg body weight of those
机译:1.一种用于治疗急性髓细胞性白血病(AML)的药物,包括悬浮有天冬酰胺酶作为活性成分的红细胞悬液。 2.根据权利要求1的药物,其中一剂悬浮液包含每kg体重50至500IU的包封的天冬酰胺酶。 2.根据权利要求1的药物,其中一剂悬浮液包含每kg体重50至200IU的包封的天冬酰胺酶。 2.根据权利要求1的药物,其中一剂悬浮液包含每kg体重80至170IU的包封的天冬酰胺酶。根据段落中任一项的药物。 1-4,其中患者是儿童,成人或老人。 6.根据权利要求5所述的药物,其中所述患者不耐受标准治疗。一种治疗急性髓细胞白血病(AML)的方法,包括给予有效量的红细胞悬浮液,其中包封有天冬酰胺酶。 8.一种用于治疗急性骨髓性白血病(AML)的方法,包括给予有效量的红细胞悬浮液,其中包封有天冬酰胺酶,其中在诱导期向患者给予一剂或多剂该悬浮液。一种治疗急性粒细胞白血病(AML)的方法,包括给予有效量的红细胞悬浮液,其中包封有天冬酰胺酶,其中在治疗阶段向患者施用一剂或多剂该悬浮液悬浮液的剂量为每千克体重.10含有50至500IU的包封的天冬酰胺酶。 10.根据权利要求9的方法,其中一剂悬浮液包含每kg体重50至200IU的包封的天冬酰胺酶。 10.根据权利要求9所述的方法,其中,所述单剂量的悬浮液包括每千克体重80-170IU的包封的天冬酰胺酶。

著录项

  • 公开/公告号RU2014142267A

    专利类型

  • 公开/公告日2016-05-20

    原文格式PDF

  • 申请/专利权人 ЭРИТЕК ФАРМА (FR);

    申请/专利号RU20140142267

  • 发明设计人 ГОДФРИН ЯНН (FR);

    申请日2013-03-21

  • 分类号A61K35/18;

  • 国家 RU

  • 入库时间 2022-08-21 14:11:23

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号