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A method for diagnosing human cell immunopathology

机译:诊断人细胞免疫病理的方法

摘要

A method for diagnosing immunopatalogy human cell, comprising the steps that produce a quantitative estimate of the immune reactivity of monocytes / macrophages, which was isolated from patients blood monocytes, activated in their culture interferon gamma (INFgamma) or interleukin (IL) -4, macrophages receiving the first and second activation type, respectively, and then determine the production of markers corresponding to the types of macrophage activation, whereupon the data obtained are compared with the results of similar studies, made with the blood of dorova donors, based on which a judgment on the condition and the individual characteristics of the immune system and present in connection with this disease and its degree of development, while in the group of the first type macrophage activation markers include proinflammatory cytokines tumor necrosis factor (TNF) alpha, and the group the second type of activation markers - SS-18 chemokine (CCL18).
机译:一种用于诊断免疫形态学人类细胞的方法,包括以下步骤:对从患者血液单核细胞中分离的单核细胞/巨噬细胞的免疫反应进行定量估计,并在其培养物中干扰素γ(INFgamma)或白介素(IL)-4激活,分别接受第一种和第二种激活类型的巨噬细胞,然后确定与巨噬细胞激活类型相对应的标记物的产生,然后将所得数据与用多罗娃供体的血液进行的类似研究的结果进行比较,基于对免疫系统的状况和个体特征的判断以及与这种疾病及其发展程度有关的判断,而在第一类巨噬细胞中,激活标记包括促炎细胞因子肿瘤坏死因子(TNF)和第二类激活标记是SS-18趋化因子(CCL18)。

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