METHOD FOR PRODUCING 'HANTA-N' TEST SYSTEM FOR DETERMINING SPECIFIC ACTIVITY OF VACCINE AGAINST HEMORRHAGIC FEVER WITH RENAL SYNDROME

摘要

FIELD: biotechnology.;SUBSTANCE: invention relates to biotechnology. Described is method for producing immuno-enzyme test system for estimation of content of immune-specific proteins of hanta-viruses as Puumala, Dobrava, Hantaan, and Seoul in vaccine preparations against hemorrhagic fever with renal syndrome (HFRS).;EFFECT: method implies production of monoclonal antibodies to Puumala and Dobrava viruses with similar sensitivity, in accordance with virus titre, for detecting antigens of each of four hanta-viruses which cause HFRS, and their subsequent sorption upon surface of polystyrene panel.;1 cl, 3 tbl, 2 ex