ANTI-HCV MONOCLONAL ANTIBODY AS THERAPEUTIC AGENT FOR MEDICAL TREATMENT AND PREVENTION OF HCV INFECTIONS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to biotechnology. What is presented is using a monoclonal antibody or its fragment containing at least one variable domain of a heavy chain and at least one variable domain of a light chain of the antibody e20 and able to bind to HCV E2 glycoprotein of the genotypes 1a, 1b, 2a, 2b or 4 for neutralising hepatitis C virus (HCV) infection.;EFFECT: present invention can find further application in the treatment and prevention of HVC infections.;6 cl, 2 tbl, 3 dwg