A bioreactor for the cultivation of cells and tissue cultures as objects as well as yeasts and bacteria

摘要

A bioreactor for the cultivation of cells and tissue cultures as well as yeasts and bacteria objects having– a trough-shaped base body (4), in each case having at least one inlet (5) and an outlet (6) in one of the side walls in connection with a reservoir with nutrient medium,– at least a horizontally disposed barrier in the trough-shaped base body (4) or as a component of the trough-shaped basic body (4) or as an area of the side wall with the outlet (6) of the trough-shaped basic body (4), wherein the distance of the outlet (6) to the bottom of the trough-shaped basic body (4) is the height of the barrier and this distance the height of the surface of the nutrient medium in the trough-shaped base body (4) is determined,– a plate-shaped support (7) with a membrane for the objects of the invention, in which the containers as constituents of the plate-shaped carrier (7) in the trough-shaped base body (4) wherein the plate-shaped carrier (7) as the containers of a wall (10) surrounding regions, the range up to a partial region (11) has an opening (12), the portion (11) corresponding to the septum (13) and extending in the region of the membrane is located, - a with the trough-shaped base body (4) tightly connected in a detachable cover (8) with septa (13) for a self-contained device,where the inlet (5) and the outlet (6) are arranged in such a way that the height of the barrier is the height of the surface of the nutrient medium in the trough-shaped base body (4) is determined, and at least the membrane of the container in the nutrient medium of the trough-shaped basic body (4) is located.