A method for the continuous production of metabolites, metabolic products and proteins from suspension cultures or culture supernatants

摘要

The present invention relates to a process for the continuous production of metabolites, metabolic products and proteins from a suspension culture (2) of microorganisms or cells, or from a culture supernatant (2) of a culture of cells or micro-organisms. In this case, the process comprises the depositing a in the suspension culture (2) or from the culture supernatant (2) in the vertical direction, sedimenting adsorber (3) for the adsorption of the metabolites, metabolic products or proteins on the bottom of a vessel (1, 10, 100, 110, 111). The vessel (1, 10, 100, 110, 111) is further supplied to the suspension culture (2) or from the culture supernatant (2) flowing through it, wherein the flow of the vessel (1, 10, 100, 110, 111) in essentially horizontal direction (h) and above the on the base of the container (1, 10, 100, 110, 111) sedimented adsorber (3) takes place.