Gel-forming system for removing kidney stone fragments

摘要

A gelling composition comprising a composition (A) containing one or more cationically crosslinkable polymers, and a composition (B) containing one or more crosslinking agents for crosslinking the cationic crosslinkable polymer (s) for use in a therapeutic method of removing kidney stones and / or kidney stone fragments from a region of a kidney containing kidney stones and / or kidney stone fragments to be removed, comprising the steps of: (i) providing the compositions (A) and (B), (ii) introducing the compositions (A) and (B ) in a region of the kidney containing kidney stones and / or kidney stone fragments to be removed, wherein the compositions (A) and (B) are introduced successively or together under conditions resulting from contact of the composition (A) with the composition (B) enable crosslinking of the cationic crosslinkable polymer or polymers, so that a crosslinked gel is formed, the di e) partially or completely enclosing kidney stones and / or kidney stone fragments to be removed, (iii) removing the cross-linked gel together with the kidney stones and / or kidney stone fragments enclosed by it from the kidney.