首页> 外国专利> PREDICTING SUSCEPTIBILITY FOR A RISK PATIENT TO DEVELOP OR REDEVELOP DIFFICULT CLOSTRIDIUM INFECTION

PREDICTING SUSCEPTIBILITY FOR A RISK PATIENT TO DEVELOP OR REDEVELOP DIFFICULT CLOSTRIDIUM INFECTION

机译:预测易患或再发展难治性念珠菌感染的风险患者的易感性

摘要

The present invention relates to a method for predicting the susceptibility, for a patient at risk, of developing or redeveloping a Clostridium difficile infection, comprising the immunoassay determination, in a stool sample from said patient, of the anti-IgA antibody level. Clostridium difficile toxin B, and to compare this level with a previously determined S reference value with two populations of patients exposed to the bacterium, one having not developed or redeveloped such an infection and the other having developed or redeveloped such an infection, - a rate lower than said reference value S signifying that the patient is a patient at increased risk of developing or redeveloping a Clostridium difficile infection, and - a rate greater than said reference value S meaning that the patient is not a patient at increased risk of developing or redeveloping Clostridium difficile infection.
机译:本发明涉及一种预测有风险的患者发生或再发展艰难梭菌感染的易感性的方法,该方法包括在所述患者的粪便样品中进行免疫测定以确定抗IgA抗体水平。艰难梭菌毒素B,并将该水平与先前确定的S参考值进行比较,以两个暴露于细菌的患者群体进行研究,一个未发生或再发展为这种感染,另一患者未发生或再发展为这种感染,低于所述参考值S表示患者是患艰难梭状芽胞杆菌感染的风险增加的患者,以及-高于所述参考值S的比率意味着患者不是患上疾病或复发风险增加的患者艰难梭菌感染。

著录项

  • 公开/公告号FR3027394A1

    专利类型

  • 公开/公告日2016-04-22

    原文格式PDF

  • 申请/专利权人 BIOMERIEUX;

    申请/专利号FR20140059996

  • 发明设计人 AGNES FOUSSADIER;MARK MILLER;

    申请日2014-10-17

  • 分类号G01N33/53;G01N33/569;

  • 国家 FR

  • 入库时间 2022-08-21 14:08:27

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