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TARGETING P53 AND ITS DNA-BINDING DOMAIN
TARGETING P53 AND ITS DNA-BINDING DOMAIN
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机译:靶向P53及其DNA结合域
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摘要
Disclosed are peptides comprising a full length p53 or a partial p53 and a mitochondrial targeting signal. Also disclosed are nucleic acids that encode peptides comprising a full length p53 or a partial p53 and a mitochondrial targeting signal. Further disclosed are methods of using the peptides and nucleic acids disclosed herein. For example, the peptides and nucleic acids can be used to treat hyperproliferative disorders.
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