N-acetylcysteine effervescent tablet and its therapeutical applications

摘要

The present invention is directed to A pharmaceutical composition in the form of an effervescent tablet comprising: (a) 1200 mg ofN-acetylcysteine; and (b) at least 1200 mg of sodium hydrogen carbonate; and (c) less than 1200 mg of anhydrous citric acid; and (d) at least one lubricant and/or glidant agent; and (e) at least one sweetener and/or flavouring agent; and said pharmaceutical composition having no sulfur smell and taste as well as a pH in the range of 4.1 and 4.4 after tablet dissolution. A manufacturing process is also disclosed. The claimed pharmaceutical composition is used in the treatment of abnormal, viscid, or inspissated mucous secretions.