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ANTI-ACETYLATED HISTONE H4 ANTIBODY

机译:抗乙酰化组蛋白H4抗体

摘要

PROBLEM TO BE SOLVED: To provide antibodies recognizing by discriminating histone H4 in which both Lys5 and Lys8 are acetylated.SOLUTION: The present invention provides an anti-acetylated histone H4 antibody which recognizes acetylated histone H4 in which Lys5 and Lys8 of the histone H4 are acetylated and comprises a heavy chain variable region and/or a light chain variable region. The heavy chain variable region has a CDRH1 consisting of a particular amino acid sequence and a CDRH3 consisting of a particular amino acid sequence, and the light chain variable region has a CDRL2 consisting of a particular amino acid sequence and CDRL3 consisting of a particular amino acid sequence.SELECTED DRAWING: None
机译:解决的问题:提供通过识别其中Lys5和Lys8都被乙酰化的组蛋白H4来识别的抗体。解决方案:本发明提供一种抗乙酰化的组蛋白H4抗体,其识别乙酰化的组蛋白H4,其中组蛋白H4的Lys5和Lys8是乙酰化并包含重链可变区和/或轻链可变区。重链可变区具有由特定氨基酸序列组成的CDRH1和由特定氨基酸序列组成的CDRH3,而轻链可变区具有由特定氨基酸序列组成的CDRL2和由特定氨基酸组成的CDRL3 sequence.SELECTED DRAWING:无

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