TRIPEPTIDE INTO WHICH DEUTERIUM AS HEPATITIS C VIRUS INHIBITOR IS INTRODUCED

摘要

PROBLEM TO BE SOLVED: To provide a hepatitis C virus inhibitor that essentially consists of deuterated tripeptide.SOLUTION: The present invention relates to a deuterated N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-N-((1R,2S)-1{[(cyclopropylsulfonyl)amino] carbonyl}-2-vinylcyclopropyl)-4-[(4-methoxy-7-chloroquinoline-1-yl)oxy]-L-prolinamide compound, a pharmaceutical composition thereof, a method for producing and a method for using thereof. The compound has a capability of inhibiting NS3 protease, and useful in treating hepatitis C virus.SELECTED DRAWING: None