Radiolabeled derivatives of 2-amino-6-fluoro-N- 5-fluoro-pyridin-3-yl pyrazolo 1,5-a pyrimidine-3-carboxamide compounds useful as ATR kinase inhibitors, Preparation of compounds and their different solid forms

摘要

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions containing the compounds of the invention; methods of treatment of various diseases, disorders, and conditions using the compounds of the invention; processes for preparing the compounds of the invention Intermediates for the preparation of the compounds of the invention; as well as solid forms of the compounds of the invention. The compounds of the invention have the formula I-1 or IA: where these variables are as defined herein.