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Systems and methods for comprehensive analysis of molecular images across multiple tumors and germline exomes
Systems and methods for comprehensive analysis of molecular images across multiple tumors and germline exomes
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机译:全面分析多个肿瘤和种系外显子组分子图像的系统和方法
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摘要
Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only.
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