A device for culturing a liver tissue has a culture chamber to which at least two flow channels, which are at least for introducing and discharging a culture medium, are connected. A gel which serves as a cell scaffold material is housed in the culture chamber. A co-culture system containing an endothelial cell-derived cell, a hepatocyte-derived cell and a mesenchymal cell is co-cultured on the gel in such a way that the co-culture system has a tubular structure.
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