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Composition comprising a cocktail of antibacterial phage and use thereof for treating bacterial infections

机译:包含抗菌噬菌体混合物的组合物及其在治疗细菌感染中的用途

摘要

The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular diabetic foot infections. More specifically, the present invention is directed to novel cocktails of bacteriophage strains F44/10, F1 25/10, F770/05, F510/08, F1 245/05, and/or variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including cutaneous ulcers associated with diabetic foot infections, caused by, e.g., Staphylococcus aureus, Pseudomonas aeruginosa, and/or Acinetobacter baumannii. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics, growth factors, or other standard, as well as non-standard, therapies for diabetic foot infections.
机译:本发明涉及用于治疗和控制细菌感染,特别是糖尿病足感染的噬菌体治疗领域。更具体地说,本发明涉及噬菌体菌株F44 / 10,F1 25/10,F770 / 05,F510 / 08,F1 245/05和/或其变体的新型混合物;以及用于治疗和预防细菌感染的方法,所述细菌感染包括由例如金黄色葡萄球菌,铜绿假单胞菌和/或鲍曼不动杆菌引起的与糖尿病足感染相关的皮肤溃疡。混合物单独或与其他疗法(例如抗生素,生长因子或其他标准以及非标准的糖尿病足感染疗法)组合用作药物组合物。

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