首页> 外国专利> Novel antifungal 5,6-dihydro-4-(difluoroethyl) phenyl -4H-pyrrolo 1,2-a 1,4 benzodiazepine and 4- (difluoroethyl) phenyl-6H-pyrrolo 1, 2-a 1,4 benzodiazepine derivatives

Novel antifungal 5,6-dihydro-4-(difluoroethyl) phenyl -4H-pyrrolo 1,2-a 1,4 benzodiazepine and 4- (difluoroethyl) phenyl-6H-pyrrolo 1, 2-a 1,4 benzodiazepine derivatives

机译:新型抗真菌5,6-二氢-4-[(二氟乙基)苯基] -4H-吡咯烷[1,2-a] [1,4]苯二氮卓和4-(二氟乙基)苯基-6H-吡咯烷[1,2-a ] [1,4]苯二氮卓衍生物

摘要

The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
机译:本发明涉及式(I)的新型化合物:其中R 1,R 2,R 3,R 4,R 5和R 6具有权利要求中定义的含义。根据本发明的化合物主要对皮肤真菌和全身性真菌感染具有活性。本发明进一步涉及制备此类新化合物的方法,包含所述化合物作为活性成分的药物组合物以及所述化合物作为药物的用途。

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