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Combined preparation containing sustained-release metformin and immediate-release HMG-CoA reductase inhibitor

机译:包含缓释二甲双胍和速释HMG-CoA还原酶抑制剂的联合制剂

摘要

The present invention relates to a combination formulation containing metformin for treating non-insulin-dependent diabetes and an HMG-CoA reductase inhibitor for treating dyslipidemia. The present invention provides a combination formulation and a method for preparing the combination formulation, wherein the combination formulation contains metformin and an HMG-CoA reductase inhibitor, and has effectively improved stability by blocking physical and chemical reactions between the active ingredients while securing the stable release of respective active ingredients.
机译:本发明涉及包含用于治疗非胰岛素依赖性糖尿病的二甲双胍和用于治疗血脂异常的HMG-CoA还原酶抑制剂的组合制剂。本发明提供了一种联合制剂和制备该联合制剂的方法,其中该联合制剂包含二甲双胍和HMG-CoA还原酶抑制剂,并通过阻断活性成分之间的物理和化学反应而有效地提高了稳定性,同时确保了稳定的释放。的有效成分。

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