Method for producing 4-borono-L-phenylalanine having 18F atoms introduced and precursor of 4-borono-L-phenylalanine having 18F atoms introduced

摘要

An object of the present invention is to provide a novel method for producing 18F-labeled BPA (4-boronophenylalanine) and a precursor of 18F-labeled BPA. An 18F-labeled BPA can be prepared by preparing and using a compound represented by the following formula: Here, R1 represents a bromo group, an iodo group, a fluoro group, a diazaborinane derivative, BX3-, or BX3-M + (X represents a halogen, and M + represents a monovalent monoatomic cation, polyatomic cation, or complex. Represents a cation).