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METHODS FOR IDENTIFYING AND TREATING INVASIVE/METASTATIC CANCERS
METHODS FOR IDENTIFYING AND TREATING INVASIVE/METASTATIC CANCERS
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机译:鉴别和治疗侵袭性/转移性癌症的方法
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摘要
Cancer invasion is a hallmark of metastasis. The mesenchymal mode of cancer cell invasion is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. Described herein are compositions and methods for assessing and treating a subject having metastatic cancer or at risk of developing metastatic cancer, e.g., metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels in the subject.
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