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LIPID NANO PARTICLES COMPRISING CATIONIC LIPID FOR DRUG DELIVERY SYSTEM
LIPID NANO PARTICLES COMPRISING CATIONIC LIPID FOR DRUG DELIVERY SYSTEM
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机译:含脂质脂质的脂质纳米颗粒,用于药物输送系统
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摘要
The present invention provides a lipid nano-particles, which allow nucleic acids to be easily introduced into cells, comprising a cationic lipid represented by formula (I);(wherein: R1 and R2 are, the same or different, alkenyl, etc, andX3 is absent or is alkyl, etc,X1 and X2 are hydrogen atoms, or are combined together to form a single bond or alkylene, andY1 is absent or anion,L1 is a single bond, etc,R3 is alkyl, etc), and the like.; 展开▼
机译:本发明提供了脂质纳米颗粒,其允许核酸容易地引入细胞中,其包含由式(I)表示的阳离子脂质;(其中:R 1 Sup>和R 2 Sup>是相同或不同的烯基等,并且 X 3 Sup>缺失或为烷基等, ListItem> < ListItem id =“ ul0001-0002” number =“ 0000”> X 1 Sup>和X 2 Sup>是氢原子,或结合在一起形成单键或亚烷基,并且 ListItem> Y 1 Sup>不存在或阴离子, ListItem> L 1 Sup>是单键,等等, ListItem> R 3 Sup>是烷基,等等)等。 ListItem> UnorderedList>; 化学>
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