首页> 外国专利> METHOD OF PREDICTING REACTION TO SORAFENIB TREATMENT USING GENE POLYMORPHISM

METHOD OF PREDICTING REACTION TO SORAFENIB TREATMENT USING GENE POLYMORPHISM

机译:基因多态性预测索拉非尼治疗的反应方法

摘要

The present invention relates to a method of predicting reaction to Sorafenib treatment using genetic polymorphism. More specifically, for the reaction to Sorafenib treatment according to the present invention, it is possible to predict the reaction of a test object to Sorafenib treatment by using an anticancer-target gene which is expressed in a biological sample of a liver cancer patient as a biomarker, whereby a proper drug is administered to a liver cancer patient and an optimal treatment effect is attained, so that inconvenience of a patient can be reduced, costs for treatment can be reduced, and an individually tailored chemotherapy can more effectively be implemented by administration of a patient-specific anticancer agent.
机译:本发明涉及使用遗传多态性预测对索拉非尼治疗的反应的方法。更具体地,对于根据本发明的对索拉非尼治疗的反应,可以通过使用在肝癌患者的生物样品中表达的抗癌靶基因来预测测试对象对索拉非尼治疗的反应。生物标志物,从而向肝癌患者施用适当的药物并获得最佳治疗效果,从而可以减少患者的不便,可以降低治疗成本,并且可以通过施用更有效地实施个性化的化疗特定于患者的抗癌药。

著录项

  • 公开/公告号US2017211147A1

    专利类型

  • 公开/公告日2017-07-27

    原文格式PDF

  • 申请/专利权人 NATIONAL CANCER CENTER;

    申请/专利号US201515302872

  • 发明设计人 JOONG-WON PAKR;YEON SU LEE;BO HYUN KIM;

    申请日2015-03-23

  • 分类号C12Q1/68;

  • 国家 US

  • 入库时间 2022-08-21 13:51:24

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