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DNA sequence, and recombinant preparation of the grass pollen allergen Lol p 4
DNA sequence, and recombinant preparation of the grass pollen allergen Lol p 4
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机译:草花粉过敏原Lol p 4的DNA序列及重组制备
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摘要
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.
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机译:本发明涉及主要草花粉变应原Lol p 4的DNA序列的提供。本发明还包括片段,具有低变应原作用的部分序列的新组合和点突变体。重组DNA分子和衍生的多肽,片段,部分序列和变体的新组合可用于花粉过敏性疾病的治疗。通过重组方法制备的蛋白质可用于花粉过敏的体外和体内诊断。
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