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Microfluidic device for generating neural cells to simulate post-stroke conditions
Microfluidic device for generating neural cells to simulate post-stroke conditions
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机译:用于产生神经细胞以模拟中风后状况的微流体装置
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摘要
This application provides devices for modeling ischemic stroke conditions. The devices can be used to culture neurons and to subject a first population of the neurons to low-oxygen conditions and a second population of neurons to normoxic conditions. The neurons are cultured on a porous barrier, and on the other side of the barrier run one or more fluid-filled channels. By flowing fluid with different oxygen levels through the channels, one can deliver desired oxygen concentrations to the cells nearest those channels.
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