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Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
Non-ionic, low osmolar contrast agents for delivery of antisense oligonucleotides and treatment of disease
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机译:非离子型低渗透压造影剂,用于递送反义寡核苷酸和治疗疾病
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摘要
Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.
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