benzamide derivatives for inhibition of abl1, abl2 and bcr-abl1 activity

摘要

Patent Summary: "Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1". The present invention relates to compounds of formula (I), wherein y, y1, r1, r2, r3 and r4 are defined in the summary of the invention, capable of inhibiting the activity of bcr-abl1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancer. 22923625v1 1/1 22923625v1