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Low molecular weight biotechnological chondroitin 6-sulfate for osteoarthritis prevention

机译:低分子量生物技术软骨素6-硫酸盐预防骨关节炎

摘要

Patent Summary: "Low molecular weight biotechnological chondroitin 6-sulfate for prevention of osteoarthritis". The present invention relates to a low molecular weight (1000 to 5000 daltons) chondroitin sulfate (cs) produced by chemical sulfation and subsequent depolymerization of an unsulfated chondroitin framework obtained by biotechnology techniques. The described dog is substantially monosulfated, especially at position 6, with very little sulfation at position 4 and with a similar mono / disaccharide ratio and charge density to those of natural dog. said biotechnological chondroitin 6-sulfate (c6s) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.
机译:专利摘要:“低分子量生物技术软骨素6硫酸盐可预防骨关节炎”。本发明涉及一种低分子量(1000至5000道尔顿)的硫酸软骨素(cs),其通过化学硫酸化和随后通过生物技术获得的未硫酸化软骨素骨架的解聚而制得。所描述的狗基本上是单硫酸盐化的,尤其是在位置6,在位置4几乎没有硫酸化,并且具有与天然狗相似的单糖/二糖比率和电荷密度。所述生物技术软骨素6-硫酸盐(c6s)可用于治疗和预防骨关节炎以及急性和慢性炎症过程。

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