pharmaceutical composition to inhibit motor neuron autophagy and its use

摘要

1/1 summary pharmaceutical composition for inhibiting autophagy of motor neurons and use thereof a pharmaceutical composition for inhibiting autophagy of motor neurons, comprising an effective amount of an active ingredient selected from the group consisting of a compound of formula (i). ), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound and combinations thereof: (i), wherein a is a C1-C5 alkyl group, optionally having one or more unsaturated bonds, and being optionally substituted by one or more substituents selected from the group consisting of -oh, = o, and C1-C3 alkyl; x is h, oh,, or; y is o or s and may optionally bond with a to form a five membered ring; and R1 is h or a substituted or unsubstituted C1-C20 alkyl group, wherein one or more -C1-C20 alkyl groups are optionally substituted by nh-or -o-.