首页> 外国专利> method for treating or preventing demyelination in a subject in need thereof; pharmaceutical composition; method for preventing progress of a demyelinating disease in a patient; method for treating progressive multiple sclerosis in a patient; and method of preventing or reducing the severity of the initiation phase of the autoimmune response in a patient who has a demyelinating disease.

method for treating or preventing demyelination in a subject in need thereof; pharmaceutical composition; method for preventing progress of a demyelinating disease in a patient; method for treating progressive multiple sclerosis in a patient; and method of preventing or reducing the severity of the initiation phase of the autoimmune response in a patient who has a demyelinating disease.

机译:在有需要的受试者中治疗或预防脱髓鞘的方法;药物组合物;预防患者脱髓鞘疾病进展的方法;治疗患者进行性多发性硬化的方法;和在患有脱髓鞘疾病的患者中预防或降低自身免疫应答起始阶段的严重性的方法。

摘要

abstract method for treating or preventing demyelination in a subject in need thereof; pharmaceutical composition; method for preventing progress of a demyelinating disease in a patient; method for treating progressive multiple sclerosis in a patient; and Method for Preventing or Reducing the Severity of the Autoimmune Response Initiation Phase in a Patient Having a Demyelinating Disease New oral pharmaceutical compositions of SAMC inhibitors, polyamine analogs and polyamine biosynthesis inhibitors, and their applications are disclosed herein. for treatment of conditions including demyelinating diseases, autoimmune diseases affecting the nervous system and other neurodegenerative conditions. 1/1
机译:治疗或预防有需要的受试者脱髓鞘的抽象方法;药物组合物;预防患者脱髓鞘疾病进展的方法;治疗患者进行性多发性硬化的方法;和用于预防或减少脱髓鞘疾病的患者中自身免疫应答开始阶段的严重性的方法和方法本文公开了SAMC抑制剂,多胺类似物和多胺生物合成抑制剂的新型口服药物组合物,及其应用。用于治疗包括脱髓鞘疾病,影响神经系统的自身免疫疾病和其他神经退行性疾病的疾病。 1/1

著录项

  • 公开/公告号BR112015016189A2

    专利类型

  • 公开/公告日2017-07-11

    原文格式PDF

  • 申请/专利权人 PATHOLOGICA LLC;

    申请/专利号BR20151116189

  • 发明设计人 JEREMY BLITZER;JOHN MCKEARN;

    申请日2014-01-08

  • 分类号A61K31/137;A61P25;A61P35;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:08

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