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immunotherapy against various haematological tumors such as acute myeloid leukemia (aml)

机译:针对各种血液肿瘤(例如急性髓细胞白血病)的免疫疗法

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapy methods. more specifically, the present invention relates to cancer immunotherapy. The present invention also relates to peptide epitopes obtained from tumor-associated cytotoxic t cells (lct), alone or in combination with other tumor-associated peptides acting as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to several novel peptide sequences and variants thereof, both derived from human tumor cell class I and class II molecules, which may be used in vaccine compositions to produce anti-tumor immune responses.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。更具体地,本发明涉及癌症免疫疗法。本发明还涉及获自肿瘤相关的细胞毒性t细胞(lct)的肽表位,其单独或与用作刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的其他肿瘤相关的肽组合。本发明涉及衍生自人I类和II类人肿瘤细胞的几种新颖的肽序列及其变体,它们可用于疫苗组合物中以产生抗肿瘤免疫应答。

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