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BICYCLIC AZA RELATIONS AS MUSCARIN M1 RECEPTOR AGONISTS

机译:作为马斯喀林M1受体激动剂的自行车氮杂关系

摘要

This invention relates to compounds (Formula (1)) that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where R1-R5, X1, X2 and p are as defined herein.
机译:本发明涉及化合物(式(1)),其是毒蕈碱M1受体的激动剂,可用于治疗毒蕈碱M1受体介导的疾病。还提供了包含所述化合物的药物组合物和所述化合物的治疗用途。提供的化合物具有下式:其中R 1 -R 5,X 1,X 2和p如本文所定义。

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