首页> 外国专利> PROCESS AND CARRIER FOR TARGETING DRUGS/DIAGNOSTICS OF PERIPHERAL AND CENTRAL NERVOUS SYSTEM.

PROCESS AND CARRIER FOR TARGETING DRUGS/DIAGNOSTICS OF PERIPHERAL AND CENTRAL NERVOUS SYSTEM.

机译:定位周围神经和中枢神经系统药物/诊断的过程和载体。

摘要

Selectively delivering drug at the targeted tissue or organ or system can save a patient from unnecessary toxicity of drug owing to its over-consumption to achieve the same desired effect by delivering drug using non-targeted formulation. This becomes crucial particularly for the potent and toxic drug molecules. Here we have developed both the process and system to selectively target peripheral and central nerve and to deliver drug more preferentially to peripheral and central nervous systems. Conjugation of a drug with a polymeric nanocarrier for targeting drug molecules in or with the delivery system in such a way that one drug molecule will help to bring the drug(s) encapsulated in those targeted systems/organs/tissues (PNS/CNS/PNS and CNS) and the other drug molecule after reaching the targeted area(s) will provide its normal action/or new effect other than the usual intended effect of the drug. The second drug can be utilized for many CNS/PNS/CNS and PNS infections including viral meningitis, against rabies infection etc. or cancer growth and such strategy or system can be utilized to build up many such new therapeutic strategies of other existing drugs which are unable to reach peripheral and central nervous system. Hence, we want to patent the process and the system developed by us to specifically deliver/target drug in the peripheral and central nervous system.
机译:在目标组织或器官或系统上选择性地输送药物可以使患者免于不必要的药物毒性,这是由于其过度消耗以通过使用非目标制剂输送药物来达到相同的预期效果。这对于有效的和有毒的药物分子尤其重要。在这里,我们已经开发了选择性靶向外周神经和中枢神经并将药物更优先地递送至外周神经和中枢神经系统的过程和系统。药物与聚合物纳米载体的结合,以一种或多种药物分子靶向药物分子的形式,使一种药物分子有助于将封装在这些靶向系统/器官/组织(PNS / CNS / PNS)中的药物带入和CNS)和其他药物分子到达目标区域后,将提供其正常作用/或除药物通常预期作用以外的新作用。第二种药物可用于许多CNS / PNS / CNS和PNS感染,包括病毒性脑膜炎,狂犬病感染等或癌症的生长,并且这种策略或系统可用于建立其他现有药物的许多此类新治疗策略,无法到达周围和中枢神经系统。因此,我们想对我们开发的过程和系统申请专利,以专门在周围和中枢神经系统中递送/靶向药物。

著录项

  • 公开/公告号IN201731033454A

    专利类型

  • 公开/公告日2017-10-20

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN201731033454

  • 申请日2017-09-21

  • 分类号A61K31/16;

  • 国家 IN

  • 入库时间 2022-08-21 13:38:19

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