A compound derived from pyrimidine piperazinil Acyl - and its Salts, Process for their PreparationPharmaceutical compositions containing them and their use in the development of Drugs that act on the central nervous system.

摘要

1. ACIL piperazinil piriminas derivative of common formula (I);Where x is o or s, R1 is alcoxi or triflumethy; R2 is tar, cyclopropene, isocyclic propene, arilo, arilalquilo, isopropene or isopropenylallyl, and it has activity in elsist EMA nerve center. (i) Compounds, wherein X may be obtained by reacting with a pyridine pyridine derivative containing a pyridine derivative, or a pyridine pyridine derivative containing a carboxyl acid or a salt or a derivative thereof. Compound (I) with X as s can be obtained by reaction (I) with X as s, or by Lawson reagent or phosphorus pentasulfide. Compound (I) has a sedative activity,It is resistant to nitrogen oxides, hypnosis or general aesthetics, and has therapeutic effects on human body and / or veterinary medicine.