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C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO2,1-C)1,4BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF
C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO2,1-C)1,4BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF
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机译:C2-氟取代的哌嗪联吡咯并[2,1-C)[1,4]苯并二氮杂丁酯的制备方法
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摘要
The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sodium phosphate buffer at pH of 7.00. The present invention further provides a process for the preparation of C2-Fluoro substituted piperazine linked pyrrolo[2,1 c][1,4]benzodiazepine of formula IX.
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