首页> 外国专利> DIHETEROARYL HISTONE DEACETYLASE INHIBITORS AND THEIR USE IN THERAPY.

DIHETEROARYL HISTONE DEACETYLASE INHIBITORS AND THEIR USE IN THERAPY.

机译:双杂环组氨酸去乙酰化抑制剂及其在治疗中的用途。

摘要

The present invention is a compound having the following formula: (Formula (I)) or a pharmaceutically acceptable salt thereof, wherein e.g. X is C or N; n is 1 to 10; each L is independently a 5- to 12-membered heteroaryl containing at least two nitrogen atoms; and W is a zinc-binding group. The compounds are useful as histone deacetylase (HDAC) inhibitors.
机译:本发明是具有下式的化合物:(式(I))或其药学上可接受的盐,例如X为C或N; n为1至10;每个L独立地是含有至少两个氮原子的5至12元杂芳基; W是锌结合基团。该化合物可用作组蛋白脱乙酰基酶(HDAC)抑制剂。

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